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Author Question: The nurse is preparing to administer trimethoprim-sulfamethoxazole (TMP-SMX) to a patient who is ... (Read 21 times)

bcretired

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on: Jul 23, 2018
The nurse is preparing to administer trimethoprim-sulfamethoxazole (TMP-SMX) to a patient who is being treated for a urinary tract infection.
 
  The nurse learns that the patient has type 2 diabetes mellitus and takes a sulfonylurea oral antidiabetic drug. The nurse will monitor this patient closely for which effect?
  a. Headaches
  b. Hypertension
  c. Hypoglycemia
  d. Superinfection

Question 2

A patient who will begin taking trimethoprim-sulfamethoxazole (TMP-SMX) asks the nurse why the combination drug is necessary. The nurse will explain that the combination is used to
 
  a. broaden the antibacterial spectrum.
  b. decrease bacterial resistance.
  c. improve the taste.
  d. minimize toxic effects.


dpost18

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Reply #1 on: Jul 23, 2018
Answer to Question 1

ANS: C
Taking oral antidiabetic agents (sulfonylurea) with sulfonamides increases the hypoglycemic effect. Sulfonylureas do not increase the incidence of headaches, hypertension, or superinfection when taken with sulfonamides. Examples of antidiabetic sulfonylurea medications are glipizide, glimepride, glyburide, tolaamide, and tolbutamide.

Answer to Question 2

ANS: B
The combination drug is used to decrease bacterial resistance to sulfonamides. It does not broaden the spectrum, improve the taste, or decrease toxicity.


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bcretired

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Reply #2 on: Jul 23, 2018
Thank you!


dpost18

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Reply #3 on: Jul 23, 2018
Always glad to help...


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