A patient who is receiving a factor VIII concentrate to treat ...

[captainjonesify]

A patient who is receiving a factor VIII concentrate to treat hemophilia A develops hives, a low-grade temperature elevation, and a stuffy nose. The nurse will prepare to:
 
  a. administer subcutaneous epinephrine.
  b. give an antipyretic medication.
  c. give oral diphenhydramine.
  d. provide respiratory support.

Question 2

A patient who is taking drugs to treat HIV has tuberculosis and has been on a four-drug regimen for 3 months without improvement in symptoms. Which drug will the nurse anticipate that the provider will add to this patient's regimen?
 
  a. bedaquiline Sirturo
  b. capreomycin Capastat Sulfate
  c. ethionamide Trecator
  d. pyridoxine

[jennafosdick]

Answer to Question 1

C
Factor VIII concentrates can cause allergic reactions, which can range from mild to severe. This patient is showing signs of a mild reaction and can be managed with an antihistamine such as diphenhydramine. Epinephrine is used if there are signs of anaphylaxis, such as wheezing and shortness of breath. Antipyretics are not indicated for low-grade fevers. Respiratory support may be necessary with severe anaphylaxis.

Answer to Question 2

A
Bedaquiline is a newer, highly effective anti-TB drug that does not accelerate the metabolism of HIV drugs and is sued for multi-drug resistant TB. Capreomycin is a second-line drug used for drug-resistant TB, but is not as effective as bedaquiline. Ethionamide is a second-line drug that is less well tolerated of all anti-TB agents and is used only when there is no alternative. Pyridoxine is given to prevent peripheral neuritis in patients taking isoniazid.

[captainjonesify]

Thanks for the timely response, appreciate it

[Sarahjh]

Excellent