This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: A nursing student asks a nurse how cancer cells become resistant to methotrexate Rheumatrex. The ... (Read 22 times)

erika

  • Hero Member
  • *****
  • Posts: 522
on: Jul 23, 2018
A nursing student asks a nurse how cancer cells become resistant to methotrexate Rheumatrex. The nurse is correct to respond by saying that cancer cells acquire resistance to methotrexate by:
 
  a. reduced production of transporter that pumps methotrexate out of cells.
  b. reduced synthesis of dihydrofolate reduc-tase.
  c. reduced uptake of methotrexate into cells.
  d. increased ability to convert the drug to a polyglutamated form.

Question 2

A patient who has urinary bladder cancer will begin receiving the chemotherapeutic agent valrubicin Valstar. What will the nurse do when administering this drug?
 
  a. Administer the drug intravenously using a large bore needle and tubing.
  b. Ensure that the tubing used to administer the drug does not contain polyvinyl chlo-ride.
  c. Monitor the patient closely for a variety of systemic drug adverse effects.
  d. Use a normal saline or sterile water diluent to dilute the medication.

Question 3

A 43-year-old patient with a strong family history of breast cancer considers taking tamoxifen Nolvadex for cancer prevention. Which assessment finding is a possible contraindication?
 
  a. History of deep vein thrombosis (DVT)
  b. History of osteoporosis
  c. Hyperlipidemia
  d. Prior hysterectomy


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

wergv

  • Sr. Member
  • ****
  • Posts: 365
Reply #1 on: Jul 23, 2018
Answer to Question 1

This is great. Thanks

Answer to Question 2

Many thanks to you.

Answer to Question 3

A
The patient's age and DVT history place her at risk for thrombosis. Tamoxifen would not be in-dicated for this patient. A prior hysterectomy, osteoporosis, and hyperlipidemia are not contrain-dications to tamoxifen.


erika

  • Member
  • Posts: 522
Reply 2 on: Jul 23, 2018
Excellent

EAN94

  • Member
  • Posts: 307
Reply 3 on: Yesterday
Wow, this really help

« previous next »
 

Did you know?

Approximately 70% of expectant mothers report experiencing some symptoms of morning sickness during the first trimester of pregnancy.

Did you know?

Vital signs (blood pressure, temperature, pulse rate, respiration rate) should be taken before any drug administration. Patients should be informed not to use tobacco or caffeine at least 30 minutes before their appointment.

Did you know?

Essential fatty acids have been shown to be effective against ulcers, asthma, dental cavities, and skin disorders such as acne.

Did you know?

Adolescents often feel clumsy during puberty because during this time of development, their hands and feet grow faster than their arms and legs do. The body is therefore out of proportion. One out of five adolescents actually experiences growing pains during this period.

Did you know?

During pregnancy, a woman is more likely to experience bleeding gums and nosebleeds caused by hormonal changes that increase blood flow to the mouth and nose.

Vacuoles in Plant Cells Are Usually Large Vacuoles in Plant Cells Are Usually Large
whitefish blastula cells whitefish blastula cells
Physical Fitness and Cancer Risk Physical Fitness and Cancer Risk
The formed elements: In this image, the red cells are red, the white cells are white, and the ... The formed elements: In this image, the red cells are red, the white cells are white, and the ...
Gap junctions. Gap junctions connect the cytoplasm of two adjacent cells. In the mammalian brain, ... Gap junctions. Gap junctions connect the cytoplasm of two adjacent cells. In the mammalian brain, ...
Stem Cells Stem Cells
Video: Egg and Sperm Formations in Animals Animation

For a complete list of videos, visit our video library