This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: A nursing student asks a nurse how cancer cells become resistant to methotrexate Rheumatrex. The ... (Read 21 times)

erika

  • Hero Member
  • *****
  • Posts: 522
on: Jul 23, 2018
A nursing student asks a nurse how cancer cells become resistant to methotrexate Rheumatrex. The nurse is correct to respond by saying that cancer cells acquire resistance to methotrexate by:
 
  a. reduced production of transporter that pumps methotrexate out of cells.
  b. reduced synthesis of dihydrofolate reduc-tase.
  c. reduced uptake of methotrexate into cells.
  d. increased ability to convert the drug to a polyglutamated form.

Question 2

A patient who has urinary bladder cancer will begin receiving the chemotherapeutic agent valrubicin Valstar. What will the nurse do when administering this drug?
 
  a. Administer the drug intravenously using a large bore needle and tubing.
  b. Ensure that the tubing used to administer the drug does not contain polyvinyl chlo-ride.
  c. Monitor the patient closely for a variety of systemic drug adverse effects.
  d. Use a normal saline or sterile water diluent to dilute the medication.

Question 3

A 43-year-old patient with a strong family history of breast cancer considers taking tamoxifen Nolvadex for cancer prevention. Which assessment finding is a possible contraindication?
 
  a. History of deep vein thrombosis (DVT)
  b. History of osteoporosis
  c. Hyperlipidemia
  d. Prior hysterectomy


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

wergv

  • Sr. Member
  • ****
  • Posts: 365
Reply #1 on: Jul 23, 2018
Answer to Question 1

This is great. Thanks

Answer to Question 2

Many thanks to you.

Answer to Question 3

A
The patient's age and DVT history place her at risk for thrombosis. Tamoxifen would not be in-dicated for this patient. A prior hysterectomy, osteoporosis, and hyperlipidemia are not contrain-dications to tamoxifen.


erika

  • Member
  • Posts: 522
Reply 2 on: Jul 23, 2018
Wow, this really help

bitingbit

  • Member
  • Posts: 323
Reply 3 on: Yesterday
Excellent

« previous next »
 

Did you know?

Illness; diuretics; laxative abuse; hot weather; exercise; sweating; caffeine; alcoholic beverages; starvation diets; inadequate carbohydrate consumption; and diets high in protein, salt, or fiber can cause people to become dehydrated.

Did you know?

On average, the stomach produces 2 L of hydrochloric acid per day.

Did you know?

It is believed that humans initially contracted crabs from gorillas about 3 million years ago from either sleeping in gorilla nests or eating the apes.

Did you know?

Anesthesia awareness is a potentially disturbing adverse effect wherein patients who have been paralyzed with muscle relaxants may awaken. They may be aware of their surroundings but unable to communicate or move. Neurologic monitoring equipment that helps to more closely check the patient's anesthesia stages is now available to avoid the occurrence of anesthesia awareness.

Did you know?

You should not take more than 1,000 mg of vitamin E per day. Doses above this amount increase the risk of bleeding problems that can lead to a stroke.

Allium cells in different phases of the cell cycle Allium cells in different phases of the cell cycle
Cycle of phage that lyses the host cells Cycle of phage that lyses the host cells
A nurse communicates with her non–English-speaking patient through an interpreter A nurse communicates with her non–English-speaking patient through an interpreter
Cultural Aspects of Being a Cancer Survivor Cultural Aspects of Being a Cancer Survivor
Nurse opens sterile package Nurse opens sterile package
Measuring the Activity of Feature Detection Cells Measuring the Activity of Feature Detection Cells
Video: Primate Evolutionary Tree Animation

For a complete list of videos, visit our video library