Author Question: What occurs when the host human responds to the injected antibodies circulating through the body? ... (Read 25 times)

burton19126 · **on:** Jul 23, 2018

What occurs when the host human responds to the injected antibodies circulating through the body?

A) The host forms antigenantibody complexes with the injected antibodies.
B) The host produces a passive immunity to the antibodies.
C) The circulating antibodies attack the host cells.
D) The host produces its own antibodies to the injected antibodies.

Question 2

A student asks the pharmacology instructor how succinylcholine differs from acetylcholine (ACh). What should the instructor respond?

A) Succinylcholine is not broken down instantly.
B) It results in a prolonged contraction of the muscle.
C) The muscle becomes hyper stimulated by succinylcholine.
D) Succinylcholine's duration of action is about 2 hours.

trampas · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

D
Feedback:
In some cases, the host human responds to the circulating injected antibodies, which are foreign proteins to the host's body, by producing its own antibodies to the injected antibodies. This results in serum sickness, a massive immune reaction that is manifested by fever, arthritis, flank pain, myalgia, and arthralgia. Options A, B, and C are incorrect answers to the question.

Answer to Question 2

A
Feedback:
Unlike endogenous ACh, succinylcholine is not broken down instantly. Succinylcholine, a depolarizing NMJ blocker, attaches to the ACh-receptor site on the muscle cell, causing a prolonged depolarization of the muscle. This depolarization causes stimulation of the muscle and muscle contraction (seen as twitching) and then as flaccid paralysis, so the contraction of the muscle is not prolonged and the muscle is incapable of being stimulated. The duration of effects of succinylcholine is 4 to 6 minutes and not 2 hours.