The patient, newly prescribed cinacalcet hydrochloride ...

[appyboo]

The patient, newly prescribed cinacalcet hydrochloride (Sensipar), asks the nurse how this drug works. What is the nurse's best response?
 
  A) It slows or blocks bone's resorption of calcium.
  B) It promotes entry of calcium into bone.
  C) It balances the effects of parathyroid hormone to lower serum calcium levels.
  D) It increases the receptor's sensitivity to extracellular calcium.

Question 2

The nurse cares for a 10-year-old child brought to the clinic for an annual checkup who is diagnosed with hypercholesterolemi a. What is the most common cause of hypercholesterolemi a in children?
 
  A) Gender
  B) Diet
  C) Familial connection
  D) Exercise

[Li Jun]

Answer to Question 1

B
Feedback:
Cinacalcet hydrochloride is a calcimimetic drug that increases the sensitivity of the calcium-sensing receptor to activation by extracellular calcium. In increasing the receptors' sensitivity, cinacalcet lowers parathyroid hormone (PTH) levels, causing a concomitant decrease in serum calcium levels. Bisphosphonates act to slow or block bone resorption; by doing this, they help to lower serum calcium levels, but they do not inhibit normal bone formation and mineralization. Calcitonins balance the effects of PTH by reducing calcium levels. Cinacalcet does not promote entry of calcium into the bone.

Answer to Question 2

C
Feedback:
Familial hypercholesterolemi a may be seen in children. Because of the importance of lipids in the developing nervous system, treatment is usually restricted to tight dietary restrictions to limit fats and calories. Gender, diet, or exercise-resistant hypercholesterolemi a is possible in children, but they are not the most common causes.

[appyboo]

Excellent

[Dominic]

Gracias!