Answer to Question 1
A
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Amphotericin B binds to ergosterol and forms holes in the membrane, causing leakage of fungal cell contents and lysis of the cell. The azole drugs bind to an enzyme that is required for synthesis of ergosterol. This action causes production of a defective cell membrane, which allows leakage of intracellular contents and destruction of the cell. Echinocandins disrupt fungal cell walls rather than fungal cell membranes. They inhibit glycan synthetase, an enzyme required for synthesis of glucan.
Answer to Question 2
B
Feedback:
Eszopiclone (Lunesta) is the first oral nonbenzodiazepine hypnotic to receive FDA approval for long-term use (12 months).
When using an interpreter, the nurse should pose questions directly to the patient, not the interpre
Varicella or chickenpox, a viral skin infection. In this photograph, the rash is beginning to form s
Coronary artery bypass graft (CABG). The grafts are often obtained from the patient’s saphenous vein
Fungal Mycelia
Normal defese mechanisms against infection