Author Question: Which drug(s) interact(s) with SSRI agents? (Select all that apply.) a. Tranylcypromine (Parnate) ... (Read 113 times)

kfurse · **on:** Jul 24, 2018

Which drug(s) interact(s) with SSRI agents? (Select all that apply.)

a. Tranylcypromine (Parnate)
b. Lithium (Eskalith)
c. Warfarin (Coumadin)
d. Furosemide (Lasix)
e. Propranolol (Inderal)

Question 2

What will the nurse include in a teaching plan for a patient with depression being treated with amitriptyline (Elavil)? (Select all that apply.)

a. Dryness of the mouth is normal; sucking on sugar free hard candy and ice chips or chewing gum may help alleviate this problem.
b. Rise slowly from a supine or sitting position to avoid dizziness and orthostatic hypotension.
c. Avoid alcohol and barbiturates.
d. If adverse effects occur, discontinue the medication.
e. An immediate elevation in mood will be noted.

Amiracle · **Reply #1 on:** Jul 24, 2018

Answer to Question 1

ANS: A, B, C, E
A 14-day lapse is recommended between MAOIs, such as Parnate, and SSRI agents.
The incidence of lithium toxicity is increased with SSRI agents. The anticoagulant effects of warfarin may be enhanced with SSRIs. The SSRIs fluvoxamine and citalopram inhibit the metabolism of beta-adrenergic blocking agents such as propranolol. Lasix does not interact with SSRI agents.

Answer to Question 2

ANS: A, B, C
Common adverse effects associated with tricyclic antidepressants are dry mouth and orthostatic hypotension. Alcohol and barbiturates should be avoided while taking tricyclic antidepressants because they enhance sedation. Adverse effects are likely to occur, and the medication should not be discontinued without the direction of the health care provider. Tricyclic antidepressants typically take several weeks to produce a therapeutic effect.