Protein kinases are enzymes that catalyze phosphorylation of target proteins at specific sites, whereas protein phosphatases catalyze removal of phosphate(s) from phosphorylated proteins. Phosphorylation and dephosphorylation can function as an on-off switch for a protein's activity, most likely through
A) the change in a protein's charge leading to a conformational change.
B) the change in a protein's charge leading to cleavage.
C) a change in the optimal pH at which a reaction will occur.
D) a change in the optimal temperature at which a reaction will occur.
Palade's use of the pulse-chase method to study protein secretion
Chemical modification of proteins
First-pass effect: (a) drugs are absorbed; (b) drugs enter hepatic portal circulation and go directl
Interaction between a CD8+ T cell and its target.
Oligosaccharides and proteins can be linked to form glycoproteins in two ways
The ras proto-oncogene encodes a signal-transduction protein that processes signals for cell divisio