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The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.
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Patients who cannot swallow may receive nutrition via a parenteral route—usually, a catheter is inserted through the chest into a large vein going into the heart.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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The first oncogene was discovered in 1970 and was termed SRC (pronounced "SARK").