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In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.
About 60% of newborn infants in the United States are jaundiced; that is, they look yellow. Kernicterus is a form of brain damage caused by excessive jaundice. When babies begin to be affected by excessive jaundice and begin to have brain damage, they become excessively lethargic.
Aspirin is the most widely used drug in the world. It has even been recognized as such by the Guinness Book of World Records.
Bacteria have been found alive in a lake buried one half mile under ice in Antarctica.
By definition, when a medication is administered intravenously, its bioavailability is 100%.