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In the ancient and medieval periods, dysentery killed about ? of all babies before they reach 12 months of age. The disease was transferred through contaminated drinking water, because there was no way to adequately dispose of sewage, which contaminated the water.
Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
More than 150,000 Americans killed by cardiovascular disease are younger than the age of 65 years.
The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
The U.S. Preventive Services Task Force recommends that all women age 65 years of age or older should be screened with bone densitometry.