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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
Hip fractures are the most serious consequences of osteoporosis. The incidence of hip fractures increases with each decade among patients in their 60s to patients in their 90s for both women and men of all populations. Men and women older than 80 years of age show the highest incidence of hip fractures.
Human stomach acid is strong enough to dissolve small pieces of metal such as razor blades or staples.
Excessive alcohol use costs the country approximately $235 billion every year.
According to the FDA, adverse drug events harmed or killed approximately 1,200,000 people in the United States in the year 2015.