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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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Signs of depression include feeling sad most of the time for 2 weeks or longer; loss of interest in things normally enjoyed; lack of energy; sleep and appetite disturbances; weight changes; feelings of hopelessness, helplessness, or worthlessness; an inability to make decisions; and thoughts of death and suicide.
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The immune system needs 9.5 hours of sleep in total darkness to recharge completely.
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On average, the stomach produces 2 L of hydrochloric acid per day.
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More than nineteen million Americans carry the factor V gene that causes blood clots, pulmonary embolism, and heart disease.