This topic contains a solution. Click here to go to the answer

Author Question: Why do you think Matias was originally diagnosed with T2DM? Why does the MD now suspect he may ... (Read 45 times)

cnetterville

  • Hero Member
  • *****
  • Posts: 547
Why do you think Matias was originally diagnosed with T2DM? Why does the MD now suspect he may actually have T1DM or LADA?
 
  What will be an ideal response?

Question 2

What are the standard diagnostic criteria for each of these diagnoses?
 
  What will be an ideal response?



Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

trampas

  • Sr. Member
  • ****
  • Posts: 320
Answer to Question 1

 He was diagnosed with type 2 diabetes one year ago due to hyperglycemia; there were probably no antibodies present at that time, meaning he met only the type 2 criteria.
 Now, the presence of antibodies GADA, IAA, and ICA indicates an autoimmune attack on the beta cells of the pancreas. The presence of antibodies makes a diagnosis of type 1 diabetes or LADA more appropriate.
 His c-peptide is 0.6, which is very low, indicating that very little insulin is being produced due to the auto-destruction of the beta cells, further confirming a type 1 diagnosis.

Answer to Question 2

Type 1 diabetes:
 Casual blood glucose above 200 mg/dL
 Fasting blood glucose above 126 mg/dL
 Oral glucose tolerance test >200 mg/dL (2-hr postprandial)
 Presence of antibodies ICA, GADA, IA-2A, and IAA
 Weight loss
 Polydipsia, polyuria, polyphagia
 C-peptide also used to help distinguish type 1 diabetes; low c-peptide indicates low or no insulin production
 HbA1c >6.5
Type 2 diabetes:
 Polydipsia, polyuria, polyphagia
 Casual blood glucose above 200 mg/dL
 Fasting blood glucose above 126 mg/dL
 Oral glucose tolerance test >200 mg/dL (2-hr postprandial)
 HbA1c >6.5
LADA: Generally, the most accepted diagnostic criteria for LADA includes the following: the presence of autoantibodies (e.g. ICA, GADA, and IA-2A), onset after age 30, and non-insulin dependent for at least six months past diagnosis




cnetterville

  • Member
  • Posts: 547
Reply 2 on: Aug 21, 2018
Great answer, keep it coming :)


dantucker

  • Member
  • Posts: 346
Reply 3 on: Yesterday
Gracias!

 

Did you know?

Cytomegalovirus affects nearly the same amount of newborns every year as Down syndrome.

Did you know?

Certain topical medications such as clotrimazole and betamethasone are not approved for use in children younger than 12 years of age. They must be used very cautiously, as directed by a doctor, to treat any child. Children have a much greater response to topical steroid medications.

Did you know?

Patients who cannot swallow may receive nutrition via a parenteral route—usually, a catheter is inserted through the chest into a large vein going into the heart.

Did you know?

The first monoclonal antibodies were made exclusively from mouse cells. Some are now fully human, which means they are likely to be safer and may be more effective than older monoclonal antibodies.

Did you know?

An identified risk factor for osteoporosis is the intake of excessive amounts of vitamin A. Dietary intake of approximately double the recommended daily amount of vitamin A, by women, has been shown to reduce bone mineral density and increase the chances for hip fractures compared with women who consumed the recommended daily amount (or less) of vitamin A.

For a complete list of videos, visit our video library