Answer to Question 1
Answer: The postsynaptic action of many neurotransmitters is terminated via reuptake of the molecule through the membrane transporter. A drug that blocks such a transporter would be expected to raise the synaptic levels of that neurotransmitter. For a disease or disorder that is thought to result from a low synaptic activity of that transmitter, blockade of the reuptake process would generate a beneficial effect.
Answer to Question 2
Answer: To modulate the internal biochemical activity of the presynaptic cell.
Antiretroviral Drugs for HIV-AIDS
Sample Workout in the Target Heart Rate Range
Process Flow Diagram of a Dual-Stage Pressure System
Centrally Acting Antispasmodic Drugs
Mechanism of Action of Antipsychotic Drugs
Cranial nerves and their target regions. (Sensory nerves are shown in blue; motor nerves, in red.)