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Author Question: Explain why the reuptake process has become a critical target for therapeutic drugs. What will be ... (Read 33 times)

fagboi

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on: Jun 22, 2018
Explain why the reuptake process has become a critical target for therapeutic drugs.
 
  What will be an ideal response?

Question 2

What is the general function of autoreceptors?
 
  What will be an ideal response?


carolinefletcherr

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Reply #1 on: Jun 22, 2018
Answer to Question 1

Answer: The postsynaptic action of many neurotransmitters is terminated via reuptake of the molecule through the membrane transporter. A drug that blocks such a transporter would be expected to raise the synaptic levels of that neurotransmitter. For a disease or disorder that is thought to result from a low synaptic activity of that transmitter, blockade of the reuptake process would generate a beneficial effect.

Answer to Question 2

Answer: To modulate the internal biochemical activity of the presynaptic cell.


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