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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.

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Serum cholesterol testing in adults is recommended every 1 to 5 years. People with diabetes and a family history of high cholesterol should be tested even more frequently.

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More than nineteen million Americans carry the factor V gene that causes blood clots, pulmonary embolism, and heart disease.

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Nitroglycerin is used to alleviate various heart-related conditions, and it is also the chief component of dynamite (but mixed in a solid clay base to stabilize it).

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There can actually be a 25-hour time difference between certain locations in the world. The International Date Line passes between the islands of Samoa and American Samoa. It is not a straight line, but "zig-zags" around various island chains. Therefore, Samoa and nearby islands have one date, while American Samoa and nearby islands are one day behind. Daylight saving time is used in some islands, but not in others—further shifting the hours out of sync with natural time.

Internal view of the heart with aorta, vena cava, and pulmonary arteries and veins. Internal view of the heart with aorta, vena cava, and pulmonary arteries and veins.
The kidney. Illustration of a sectioned kidney, which reveals its internal features. The kidney. Illustration of a sectioned kidney, which reveals its internal features.
Technology Gives Us Options with Different Environmental Consequences Technology Gives Us Options with Different Environmental Consequences
A comparison of adiabatic and environmental cooling rates. A comparison of adiabatic and environmental cooling rates.
cow internal cow internal
Transcriptome analysis Transcriptome analysis
Video: Phases of an Action Potential - Resting Potential, Threshold, Rising, Falling, & Recovery Phases

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