Studies of gene mutation frequencies have shown that ________.

[RODY.ELKHALIL]

Question 1

In eukaryotes, homologous recombination is initiated by ________.
◦ Rad51 generating double-stranded DNA breaks
◦ RecA, RecB, and RecC generating single-stranded DNA breaks
◦ Spo11 generating double-stranded DNA breaks
◦ p53 generating single-stranded DNA breaks
◦ ATM signaling double-stranded DNA breaks

Question 2

Studies of gene mutation frequencies have shown that ________.
◦ mutations are rare, and genomes are generally stable
◦ mutation are common and adaptive
◦ mutation frequencies are consistent between organisms, and each region of DNA is equally susceptible to random mutations
◦ mutations occur only at certain nucleotides and not others
◦ mutations affect RNA, but do not change DNA sequence

[AmberC1996]

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[RODY.ELKHALIL]

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