The crossover fixation model predicts that:

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Question 1

Thalassemias are primarily caused by:

◦ base substitutions that alter α or β globin genes.
◦ deletions that eliminate α or β globin genes.
◦ base substitutions that alter γ or δ globin genes.
◦ deletions that eliminate γ or δ globin genes.
◦ insertions that alter α or β globin genes.

Question 2

The crossover fixation model predicts that:

◦ any sequence of DNA that is not under selective pressure will be taken over by a series of identical tandem repeats.
◦ any sequence of DNA that is under selective pressure will be taken over by a series of identical tandem repeats.
◦ any sequence of DNA that is not under selective pressure will be taken over by a series of nonidentical tandem repeats.
◦ any sequence of DNA that is under selective pressure will be taken over by a series of nonidentical tandem repeats.
◦ any sequence of DNA that is not under selective pressure will gradually reduce its frequency of crossing over.

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