Author Question: How does irritation or injury of endothelial cells lead to lowered LDL levels? What will be an ... (Read 19 times)

nummyann

  • Hero Member
  • *****
  • Posts: 576
How does irritation or injury of endothelial cells lead to lowered LDL levels?
 
  What will be an ideal response?

Question 2

What are endothelial cells?
 
  What will be an ideal response?



Chocorrol77

  • Sr. Member
  • ****
  • Posts: 313
Answer to Question 1

Irritation or injury stimulates the inflammatory response and calls the white blood cells to action, the leukocytes. Leukocytes called monocytes are attracted to vascular adhesion molecules on the endothelial cells and penetrate the vascular wall. Once inside, these monocytes transform into macrophages that eat modified LDL (low density lipoprotein), otherwise known as bad cholesterol.

Answer to Question 2

The inner lining of the vascular wall, the intima, is composed of endothelial cells. These cells form a type of Teflon lining that prevents other cells from sticking to them. However, with sufficient irritation or injury, these endothelial cells become compromised.



Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
 

Did you know?

The training of an anesthesiologist typically requires four years of college, 4 years of medical school, 1 year of internship, and 3 years of residency.

Did you know?

Women are 50% to 75% more likely than men to experience an adverse drug reaction.

Did you know?

Multiple sclerosis is a condition wherein the body's nervous system is weakened by an autoimmune reaction that attacks the myelin sheaths of neurons.

Did you know?

Medication errors are three times higher among children and infants than with adults.

Did you know?

In most climates, 8 to 10 glasses of water per day is recommended for adults. The best indicator for adequate fluid intake is frequent, clear urination.

For a complete list of videos, visit our video library