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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
As the western states of America were settled, pioneers often had to drink rancid water from ponds and other sources. This often resulted in chronic diarrhea, causing many cases of dehydration and death that could have been avoided if clean water had been available.
In 1844, Charles Goodyear obtained the first patent for a rubber condom.
After 5 years of being diagnosed with rheumatoid arthritis, one every three patients will no longer be able to work.
Many medications that are used to treat infertility are injected subcutaneously. This is easy to do using the anterior abdomen as the site of injection but avoiding the area directly around the belly button.