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In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.
The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.
Hip fractures are the most serious consequences of osteoporosis. The incidence of hip fractures increases with each decade among patients in their 60s to patients in their 90s for both women and men of all populations. Men and women older than 80 years of age show the highest incidence of hip fractures.
Medications that are definitely not safe to take when breastfeeding include radioactive drugs, antimetabolites, some cancer (chemotherapy) agents, bromocriptine, ergotamine, methotrexate, and cyclosporine.
By definition, when a medication is administered intravenously, its bioavailability is 100%.