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In 1864, the first barbiturate (barbituric acid) was synthesized.
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In the United States, there is a birth every 8 seconds, according to the U.S. Census Bureau's Population Clock.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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More than 30% of American adults, and about 12% of children utilize health care approaches that were developed outside of conventional medicine.
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The first war in which wide-scale use of anesthetics occurred was the Civil War, and 80% of all wounds were in the extremities.