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Sildenafil (Viagra®) has two actions that may be of consequence in patients with heart disease. It can lower the blood pressure, and it can interact with nitrates. It should never be used in patients who are taking nitrates.
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To maintain good kidney function, you should drink at least 3 quarts of water daily. Water dilutes urine and helps prevent concentrations of salts and minerals that can lead to kidney stone formation. Chronic dehydration is a major contributor to the development of kidney stones.
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The FDA recognizes 118 routes of administration.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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By definition, when a medication is administered intravenously, its bioavailability is 100%.