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Ether was used widely for surgeries but became less popular because of its flammability and its tendency to cause vomiting. In England, it was quickly replaced by chloroform, but this agent caused many deaths and lost popularity.
Asthma cases in Americans are about 75% higher today than they were in 1980.
Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.
Certain topical medications such as clotrimazole and betamethasone are not approved for use in children younger than 12 years of age. They must be used very cautiously, as directed by a doctor, to treat any child. Children have a much greater response to topical steroid medications.
In 1864, the first barbiturate (barbituric acid) was synthesized.