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Signs and symptoms of a drug overdose include losing consciousness, fever or sweating, breathing problems, abnormal pulse, and changes in skin color.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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Drying your hands with a paper towel will reduce the bacterial count on your hands by 45–60%.