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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
People with high total cholesterol have about two times the risk for heart disease as people with ideal levels.
There are approximately 3 million unintended pregnancies in the United States each year.
Malaria mortality rates are falling. Increased malaria prevention and control measures have greatly improved these rates. Since 2000, malaria mortality rates have fallen globally by 60% among all age groups, and by 65% among children under age 5.
Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.