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Once thought to have neurofibromatosis, Joseph Merrick (also known as "the elephant man") is now, in retrospect, thought by clinical experts to have had Proteus syndrome. This endocrine disease causes continued and abnormal growth of the bones, muscles, skin, and so on and can become completely debilitating with severe deformities occurring anywhere on the body.
Thyroid conditions cause a higher risk of fibromyalgia and chronic fatigue syndrome.
The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
Human kidneys will clean about 1 million gallons of blood in an average lifetime.
In 1835 it was discovered that a disease of silkworms known as muscardine could be transferred from one silkworm to another, and was caused by a fungus.