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Long-term mental and physical effects from substance abuse include: paranoia, psychosis, immune deficiencies, and organ damage.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Certain chemicals, after ingestion, can be converted by the body into cyanide. Most of these chemicals have been removed from the market, but some old nail polish remover, solvents, and plastics manufacturing solutions can contain these substances.
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Pubic lice (crabs) are usually spread through sexual contact. You cannot catch them by using a public toilet.