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In 1885, the Lloyd Manufacturing Company of Albany, New York, promoted and sold "Cocaine Toothache Drops" at 15 cents per bottle! In 1914, the Harrison Narcotic Act brought the sale and distribution of this drug under federal control.
As many as 28% of hospitalized patients requiring mechanical ventilators to help them breathe (for more than 48 hours) will develop ventilator-associated pneumonia. Current therapy involves intravenous antibiotics, but new antibiotics that can be inhaled (and more directly treat the infection) are being developed.
The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.
In 1844, Charles Goodyear obtained the first patent for a rubber condom.
The Romans did not use numerals to indicate fractions but instead used words to indicate parts of a whole.