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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
Intradermal injections are somewhat difficult to correctly administer because the skin layers are so thin that it is easy to accidentally punch through to the deeper subcutaneous layer.
There are more sensory neurons in the tongue than in any other part of the body.
The longest a person has survived after a heart transplant is 24 years.
Human stomach acid is strong enough to dissolve small pieces of metal such as razor blades or staples.