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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
Approximately 15–25% of recognized pregnancies end in miscarriage. However, many miscarriages often occur before a woman even knows she is pregnant.
There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
More than 30% of American adults, and about 12% of children utilize health care approaches that were developed outside of conventional medicine.
In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.