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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Throughout history, plants containing cardiac steroids have been used as heart drugs and as poisons (e.g., in arrows used in combat), emetics, and diuretics.
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Bacteria have been found alive in a lake buried one half mile under ice in Antarctica.
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Thyroid conditions may make getting pregnant impossible.
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By definition, when a medication is administered intravenously, its bioavailability is 100%.