A 29-year-old female has been admitted to the emergency ...

[pane00]

A 29-year-old female has been admitted to the emergency department following a suicide attempt by overdose of acetaminophen. What changes in the client's liver and diagnostic results would the care team most likely anticipate?
 
  A)
  Hepatocellular necrosis evidenced by increased ALT and AST levels
  B)
  Allergic inflammation accompanied by an increase in serum IgE and basophils
  C)
  Cholestatic reaction with increased bilirubin count
  D)
  Rapid onset of hepatitis and increased GGT, ALT, and bilirubin

Question 2

A 28-year-old male who is 611 tall has a diagnosis of acromegaly. The man is explaining to a curious but sympathetic coworker exactly what accounts for his extraordinary height.
 
  Which of the following explanations demonstrates a sound understanding of his health problem?
  A)
  My pituitary gland produced a much higher than normal amount of growth hormone when I was a child.
  B)
  A tumor in my brain threw off my hormone levels after I was finished adolescence.
  C)
  My liver is malfunctioning and produces too many of the hormones that ultimately cause growth.
  D)
  The high sugar levels that go along with my diabetes made my pituitary gland overproduce the hormones that cause you to grow.

[fatboyy09]

Answer to Question 1

Ans:
A

Feedback:

Acetaminophen is commonly implicated in cases of direct hepatotoxicity, a situation that is characterized by hepatocellular necrosis and increased ALT and AST levels. An allergic-type reaction is associated with idiosyncratic drug reactions, and cholestatic reactions and development of hepatitis are not noted to be associated with acetaminophen.

Answer to Question 2

Ans:
B

Feedback:

Acromegaly is associated with adult onset and nearly always involves an adenoma. Increased GH as a child and liver dysfunction are not noted contributors to acromegaly. High levels of GH can cause overproduction of insulin and eventual diabetes, but diabetes does not itself lead to acromegaly.