A 44-year-old Caucasian woman is being treated in an airport ...

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A 44-year-old Caucasian woman is being treated in an airport infirmary after she developed a painful, swollen leg during a transatlantic flight in economy class.
 
  The woman is suspected of having deep vein thrombosis (DVT) and is questioning the paramedics about why this might be the case, given that she has twice previously had similar experiences. Which of the following teaching points by the airport medical staff would be most appropriate?
  A)
  A lot of Caucasian people have a genetic mutation that causes platelets to stick to their blood vessel walls.
  B)
  There is a genetic disorder that causes many Caucasians to form more clots in their blood vessels.
  C)
  A lot of Caucasians have an inherited inability to dissolve clots that form in their bodies.
  D)
  Your doctor might be able to tell you if you've inherited a predisposition to bleeding in your veins.

Question 2

A 66-year-old female patient has presented to the emergency department because of several months of intermittently bloody stool that has recently become worse.
 
  The woman has since been diagnosed with a gastrointestinal bleed secondary to overuse of nonsteroidal anti-inflammatory drugs that she takes for her arthritis. The health care team would realize that which of the following situations is most likely to occur?
  A)
  The woman has depleted blood volume due to her ongoing blood loss.
  B)
  She will have iron deficiency anemia due to depletion of iron stores.
  C)
  The patient will be at risk for cardiovascular collapse or shock.
  D)
  She will have delayed reticulocyte release.

[tennis14576]

Answer to Question 1

Ans:
C

Feedback:

All of the listed responses refer to the Leiden mutation, which is best characterized as an inhibition of normal clot dissolution due to factor V defects. It does not involve platelet aggregation or adhesion or excess bleeding. It is better characterized as decreased clot dissolution rather than increased clot formation.

Answer to Question 2

Ans:
B

Feedback:

Ongoing blood loss is associated with iron deficiency anemia due to the depletion of iron stores. She is unlikely to have a depleted blood volume or be at risk for shock, situations more commonly associated with traumatic, sudden blood loss. There would not likely be a delay in the release of reticulocytes.

[jhjkgdfhk]

Excellent

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