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Certain topical medications such as clotrimazole and betamethasone are not approved for use in children younger than 12 years of age. They must be used very cautiously, as directed by a doctor, to treat any child. Children have a much greater response to topical steroid medications.
In 1885, the Lloyd Manufacturing Company of Albany, New York, promoted and sold "Cocaine Toothache Drops" at 15 cents per bottle! In 1914, the Harrison Narcotic Act brought the sale and distribution of this drug under federal control.
Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.
More than 30% of American adults, and about 12% of children utilize health care approaches that were developed outside of conventional medicine.
By definition, when a medication is administered intravenously, its bioavailability is 100%.