Author Question: Who should select the coagulation instruments for a given laboratory? a. Laboratory director b. ... (Read 62 times)

jman1234 · **on:** Jun 25, 2018

Who should select the coagulation instruments for a given laboratory?

a. Laboratory director
b. Department manager
c. Clinical laboratory scientists
d. All of the previously listed individuals working together

Question 2

Aspirin-induced bleeding and Willebrand disease (VWD), type 1, are detected reliably by:

a. Bleeding time
b. Point-of-care testing (POCT)
c. PFA 100 Platelet Function Analyzer
d. Nephelometry

morrie123456 · **Reply #1 on:** Jun 25, 2018

Answer to Question 1

ANS: D
Decisions regarding purchase of new equipment for the clinical laboratory should involve all those individuals listed. It also should be made in conjunction with the medical staff so that tests that are the most appropriate for the clinical situations encountered by the specific clinical laboratory are available.

Answer to Question 2

ANS: C
The PFA 100 Platelet Function Analyzer assesses platelet dysfunction. Aspirin and VWD both negatively affect platelet function, although by entirely different mechanisms. Aspirin acetylates cyclooxygenase, thus preventing the eventual production of thromboxane A2, an important platelet agonist. In type 1 VWD, von Willebrand factor (VWF) is decreased and therefore platelet adhesion is abnormal. The bleeding time is not a reliable test for platelet function, although it can be abnormal (prolonged).