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Author Question: All of the following serine proteases are bound and inhibited by antithrombin except: a. Xa b. ... (Read 30 times)

rayancarla1

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on: Jun 25, 2018
All of the following serine proteases are bound and inhibited by antithrombin except:
 
  a. Xa
  b. IXa
  c. VIIa
  d. XIa

Question 2

Why is the platelet count monitored daily for a patient receiving heparin therapeutically?
 
  a. Platelets increase when a patient is overheparinized.
  b. Platelets decrease when a patient is overheparinized.
  c. A significant decrease in the platelet count is evidence for heparin-induced thrombocytopenia.
  d. A significant increase in the platelet count is early evidence for heparin-induced thrombocytosis.


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dyrone

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Reply #1 on: Jun 25, 2018
Answer to Question 1

ANS: C
Antithrombin covalently binds and inhibits XIIa, XIa, Xa, IXa, and thrombin. It does not bind VIIa.

Answer to Question 2

ANS: C
A decrease of 40 or greater in the platelet count, even if the platelet count remains in the reference range, is evidence for heparin-induced thrombocytopenia. This is a serious consequence, and unfractionated heparin therapy must be immediately stopped and replaced with a direct thrombin inhibitor.


rayancarla1

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Reply 2 on: Jun 25, 2018
Thanks for the timely response, appreciate it

aliotak

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Reply 3 on: Yesterday
Wow, this really help

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