This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: A patient has an elevated thrombin time and normal reptilase time. Which of the following situations ... (Read 62 times)

mia

  • Hero Member
  • *****
  • Posts: 564
on: Jun 25, 2018
A patient has an elevated thrombin time and normal reptilase time. Which of the following situations is most likely?
 
  a. Heparin therapy
  b. Low fibrinogen
  c. Elevated fibrin split products
  d. Dysfibrinogenemia

Question 2

A prolonged PTT is corrected when mixed with normal plasma and tested immediately and after a 2-hour incubation. Which test (or tests) should be performed next?
 
  a. Bethesda titer
  b. High phospholipid PTT
  c. Anti-Xa assay
  d. Factor VIII and IX assays


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

durant1234

  • Sr. Member
  • ****
  • Posts: 338
Reply #1 on: Jun 25, 2018
Answer to Question 1

ANS: A
Heparin prolongs the thrombin time but does not prolong the reptilase time. A low fibrinogen, elevated fibrin split products, and dysfibrinogenemia prolong both, although differences exist in sensitivity to some of these between the two tests.

Answer to Question 2

ANS: D
This pattern suggests a factor deficiency, and factor VIII and IX assays should be performed. The Bethesda titer is performed when a specific factor inhibitor is present; no evidence exists for this because the PTT on the incubated 1:1 mix did not prolong. High phospholipid PTT testing is done to confirm the lupus anticoagulant; this is not present because the immediate 1:1 mix on this sample corrected. No reason exists to perform an anti-Xa assay, often used to monitor LMWH.


mia

  • Member
  • Posts: 564
Reply 2 on: Jun 25, 2018
Excellent

phuda

  • Member
  • Posts: 348
Reply 3 on: Yesterday
Great answer, keep it coming :)

« previous next »
 

Did you know?

Vaccines cause herd immunity. If the majority of people in a community have been vaccinated against a disease, an unvaccinated person is less likely to get the disease since others are less likely to become sick from it and spread the disease.

Did you know?

It is believed that the Incas used anesthesia. Evidence supports the theory that shamans chewed cocoa leaves and drilled holes into the heads of patients (letting evil spirits escape), spitting into the wounds they made. The mixture of cocaine, saliva, and resin numbed the site enough to allow hours of drilling.

Did you know?

For high blood pressure (hypertension), a new class of drug, called a vasopeptidase blocker (inhibitor), has been developed. It decreases blood pressure by simultaneously dilating the peripheral arteries and increasing the body's loss of salt.

Did you know?

Human neurons are so small that they require a microscope in order to be seen. However, some neurons can be up to 3 feet long, such as those that extend from the spinal cord to the toes.

Did you know?

Calcitonin is a naturally occurring hormone. In women who are at least 5 years beyond menopause, it slows bone loss and increases spinal bone density.

Chest Configurations, Normal Adult, Barrel Chest, Pectus Carinatum, Pectus Excavatum Chest Configurations, Normal Adult, Barrel Chest, Pectus Carinatum, Pectus Excavatum
Time course and phases of a nerve cell going from resting potential to action potential Time course and phases of a nerve cell going from resting potential to action potential
Greet a First-Time Client With a Firm Handshake. Greet a First-Time Client With a Firm Handshake.
Normal heart valves Normal heart valves
Normal red blood cells (round) and sickled red blood cells Normal red blood cells (round) and sickled red blood cells
Variations in patient response to drugs Variations in patient response to drugs
Video: Green alga life cycle Animation

For a complete list of videos, visit our video library