Author Question: All of the following are functions of thrombin except: a. Activates factors V and VIII b. ... (Read 79 times)

lb_gilbert · **on:** Jun 25, 2018

All of the following are functions of thrombin except:

a. Activates factors V and VIII
b. Activates plasminogen
c. Activates factor XIII
d. Initiates platelet aggregation

Question 2

What is the role cofactors play in the procoagulant process?

a. Bind fibrinolytic factors to slow down lysis of the clot
b. Bind Ca2+ to form a bridge with platelet phospholipids
c. Bind to their specific activated serine protease to stabilize the protease and increase its activity
d. Bind to collagen to aid in platelet adhesion

adammoses97 · **Reply #1 on:** Jun 25, 2018

Answer to Question 1

ANS: B
Thrombin does not activate plasminogen. It does perform all of the other functions listed.

Answer to Question 2

ANS: C
Cofactors bind to their specific activated serine protease to stabilize the protease and increase its activity. One example is the binding of the cofactor Va to factor Xa, which then magnifies the activity of factor Xa to activate prothrombin.