Author Question: What leukemia is most likely in a patient whose bone marrow is composed of predominantly large, ... (Read 134 times)

jessicacav · **on:** Jun 25, 2018

What leukemia is most likely in a patient whose bone marrow is composed of predominantly large, multinucleated, dysplastic erythroid precursors?

a. Acute myelomonocytic leukemia
b. Acute megakaryocytic leukemia
c. Acute erythroleukemia
d. Acute myeloid leukemia with minimal maturation

Question 2

A child has monotonous blasts in the peripheral blood that have scant blue cytoplasm. They are cALLa (CD10) positive. Which form of acute lymphoblastic leukemia is most likely?

a. Immature B cell
b. Immature T cell
c. Mature B cell
d. Mature T cell

IRincones · **Reply #1 on:** Jun 25, 2018

Answer to Question 1

ANS: C
The bone marrow erythroid precursors display significant dysplastic features, including multinucleation, megaloblastoid asynchrony, and vacuolization, in acute erythroleukemia. Abnormal megakaryocytes may also be present.

Answer to Question 2

ANS: A
cALLa (CD10) is expressed on the surface of cells in immature B-cell acute lymphoblastic leukemia. This marker is not present on the other forms of acute lymphoblastic leukemia that are listed.