Myelodysplastic syndromes sometimes share similar peripheral and ...

[Alygatorr01285]

Myelodysplastic syndromes sometimes share similar peripheral and bone marrow cellularity with all of the following except:
 
  a. Vitamin B12 deficiency
  b. Aplastic anemia
  c. Acute leukemia
  d. Folate deficiency

Question 2

Therapy-related myelodysplastic syndrome follows what type of treatment?
 
  a. Certain antibiotic agents for severe infection
  b. Human growth factors such as CSF-GM
  c. Corticosteroid agents for immune disorders
  d. Chemotherapy and radiation for cancer

[al]

Answer to Question 1

ANS: B
The bone marrow in aplastic anemia is hypocellular, containing primarily fat cells, lymphocytes, and plasma cells. Cytopenias exist in the peripheral blood, but cell morphology is normal and no immature cells are present. The myelodysplastic syndromes, in general, have a hyperplastic bone marrow but cytopenia (or cytopenias) in peripheral blood. These two findings can also be seen in acute leukemia and both vitamin B12 and folate deficiencies.

Answer to Question 2

ANS: D
Secondary (or therapy related) myelodysplastic syndrome occurs after chemotherapy and radiation treatment for cancer.

[Alygatorr01285]

Thanks for the timely response, appreciate it

[AngeliqueG]

Gracias!