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Author Question: Monospecific Coombs sera indicates that a patient's red cells have complement coating them. Which of ... (Read 10 times)

joblessjake

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on: Jun 25, 2018
Monospecific Coombs sera indicates that a patient's red cells have complement coating them. Which of the following red cell morphology would be more likely?
 
  a. Spherocytes
  b. Schistocytes
  c. Acanthocytes
  d. Agglutination

Question 2

All of the following have been linked to excess erythrocyte destruction except:
 
  a. Drugs.
  b. IgM autoimmune antibodies
  c. Immunoglobulin E (IgE) alloantibodies
  d. IgG alloantibodies


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aruss1303

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Reply #1 on: Jun 25, 2018
Answer to Question 1

ANS: D
When only complement is present on the membrane, giving a positive direct antiglobulin test using monospecific Coombs sera, a cold agglutinin is most likely present. Agglutination of red blood cells (RBCs) would be seen on the blood provided it is at room temperature.

Answer to Question 2

ANS: C
Of the items listed, only IgE antibodies have not been associated with excess red cell destruction.


joblessjake

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Reply 2 on: Jun 25, 2018
Great answer, keep it coming :)

LVPMS

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Reply 3 on: Yesterday
Excellent

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