This topic contains a solution. Click here to go to the answer

Author Question: A urine sediment stains with Prussian blue. The patient probably has: a. Hemoglobinemia b. A ... (Read 111 times)

olgavictoria

  • Hero Member
  • *****
  • Posts: 528
A urine sediment stains with Prussian blue. The patient probably has:
 
  a. Hemoglobinemia
  b. A membrane defect
  c. Compensated hemolysis
  d. Extravascular hemolysis

Question 2

Which of the following are typical findings in extravascular hemolysis?
 
  a. Increased serum and urine conjugated bilirubin
  b. Increased serum and urine unconjugated bilirubin
  c. Increased serum unconjugated bilirubin and increased urine urobilinogen
  d. Decreased urine and stool conjugated bilirubin



Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

sultana.d

  • Sr. Member
  • ****
  • Posts: 320
Answer to Question 1

ANS: A
When the amount of free hemoglobin exceeds the capacity of plasma salvage systems (e.g., haptoglobin, hemopexin), free hemoglobin can be found in plasma. This hemoglobin is filtered through the kidney; some of the iron will be released and taken up by renal tubular cells that are eventually sloughed off into the urine. The iron can be detected in these renal tubular epithelial cells by giving a positive Prussian blue stain.

Answer to Question 2

ANS: C
During the process of extravascular hemolysis, macrophages phagocytize and break down hemoglobin into its various component parts. Unconjugated bilirubin is thus increased. This is taken to the liver, where it is conjugated. Bacteria in the gut oxidize conjugated bilirubin into various water-soluble compounds that together are called urobilinogen. Some of this is reabsorbed into the plasma and because of its water solubility will be filtered by the renal glomerulus and excreted into urine. This results in an increase in urobilinogen in the urine.




olgavictoria

  • Member
  • Posts: 528
Reply 2 on: Jun 25, 2018
Wow, this really help


hollysheppard095

  • Member
  • Posts: 339
Reply 3 on: Yesterday
Excellent

 

Did you know?

Between 1999 and 2012, American adults with high total cholesterol decreased from 18.3% to 12.9%

Did you know?

All adverse reactions are commonly charted in red ink in the patient's record and usually are noted on the front of the chart. Failure to follow correct documentation procedures may result in malpractice lawsuits.

Did you know?

It is widely believed that giving a daily oral dose of aspirin to heart attack patients improves their chances of survival because the aspirin blocks the formation of new blood clots.

Did you know?

The National Institutes of Health have supported research into acupuncture. This has shown that acupuncture significantly reduced pain associated with osteoarthritis of the knee, when used as a complement to conventional therapies.

Did you know?

Essential fatty acids have been shown to be effective against ulcers, asthma, dental cavities, and skin disorders such as acne.

For a complete list of videos, visit our video library