Author Question: The acid elution test for hemoglobin F was performed on a patient sample, and examination of the ... (Read 57 times)

fbq8i

  • Hero Member
  • *****
  • Posts: 527
The acid elution test for hemoglobin F was performed on a patient sample, and examination of the slide revealed an uneven distribution of hemoglobin F within the erythrocytes. Control slides were acceptable.
 
  Which of the following is associated with this observation?
 
  a. Iron deficiency anemia
  b. Sickle cell anemia
  c. Pernicious anemia
  d. Hereditary persistence of fetal hemoglobin

Question 2

The following are preliminary screening test results. Name the suspected disorder associated with each finding, and explain how you would confirm each.
 
  a. Positive sugar-water test
  b. Positive hemolysis after both incubation periods
  c. Normal sTFR levels
  d. Many spherocytes noted on PB smear
  e. Blasts noted on PB smear
 
  What will be an ideal response?



Chou

  • Sr. Member
  • ****
  • Posts: 335
Answer to Question 1

Correct Answer: B

Answer to Question 2

Answer:
a. Suspected disorder: PNH; confirmation: flow cytometry for an absence of CD55 and CD59
b. Suspected disorder: PCH; confirmation: Donath-Landsteiner test. Further testing is not warranted.
c. Suspected disorder: anemia of chronic disease; confirmation: increased ferritin; low iron and TIBC
d. Suspected disorder: hereditary spherocytosis or hemolysis; confirmation: osmotic fragility
e. Suspected disorder: acute leukemia; confirmation: bone marrow aspirate and cytochemical stains and immunophenotyping



Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
 

Did you know?

The newest statin drug, rosuvastatin, has been called a superstatin because it appears to reduce LDL cholesterol to a greater degree than the other approved statin drugs.

Did you know?

It is widely believed that giving a daily oral dose of aspirin to heart attack patients improves their chances of survival because the aspirin blocks the formation of new blood clots.

Did you know?

Acute bronchitis is an inflammation of the breathing tubes (bronchi), which causes increased mucus production and other changes. It is usually caused by bacteria or viruses, can be serious in people who have pulmonary or cardiac diseases, and can lead to pneumonia.

Did you know?

In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.

Did you know?

Multiple sclerosis is a condition wherein the body's nervous system is weakened by an autoimmune reaction that attacks the myelin sheaths of neurons.

For a complete list of videos, visit our video library