« previous next »

Author Question: The acid elution test for hemoglobin F was performed on a patient sample, and examination of the ... (Read 47 times)

fbq8i

  • Hero Member
  • *****
  • Posts: 527
on: Jun 25, 2018
The acid elution test for hemoglobin F was performed on a patient sample, and examination of the slide revealed an uneven distribution of hemoglobin F within the erythrocytes. Control slides were acceptable.
 
  Which of the following is associated with this observation?
 
  a. Iron deficiency anemia
  b. Sickle cell anemia
  c. Pernicious anemia
  d. Hereditary persistence of fetal hemoglobin

Question 2

The following are preliminary screening test results. Name the suspected disorder associated with each finding, and explain how you would confirm each.
 
  a. Positive sugar-water test
  b. Positive hemolysis after both incubation periods
  c. Normal sTFR levels
  d. Many spherocytes noted on PB smear
  e. Blasts noted on PB smear
 
  What will be an ideal response?


Chou

  • Sr. Member
  • ****
  • Posts: 335
Reply #1 on: Jun 25, 2018
Answer to Question 1

Correct Answer: B

Answer to Question 2

Answer:
a. Suspected disorder: PNH; confirmation: flow cytometry for an absence of CD55 and CD59
b. Suspected disorder: PCH; confirmation: Donath-Landsteiner test. Further testing is not warranted.
c. Suspected disorder: anemia of chronic disease; confirmation: increased ferritin; low iron and TIBC
d. Suspected disorder: hereditary spherocytosis or hemolysis; confirmation: osmotic fragility
e. Suspected disorder: acute leukemia; confirmation: bone marrow aspirate and cytochemical stains and immunophenotyping


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
« previous next »
 

Did you know?

Walt Disney helped combat malaria by making an animated film in 1943 called The Winged Scourge. This short film starred the seven dwarfs and taught children that mosquitos transmit malaria, which is a very bad disease. It advocated the killing of mosquitos to stop the disease.

Did you know?

As many as 28% of hospitalized patients requiring mechanical ventilators to help them breathe (for more than 48 hours) will develop ventilator-associated pneumonia. Current therapy involves intravenous antibiotics, but new antibiotics that can be inhaled (and more directly treat the infection) are being developed.

Did you know?

Intradermal injections are somewhat difficult to correctly administer because the skin layers are so thin that it is easy to accidentally punch through to the deeper subcutaneous layer.

Did you know?

Every 10 seconds, a person in the United States goes to the emergency room complaining of head pain. About 1.2 million visits are for acute migraine attacks.

Did you know?

Though “Krazy Glue” or “Super Glue” has the ability to seal small wounds, it is not recommended for this purpose since it contains many substances that should not enter the body through the skin, and may be harmful.

Electrocardiography. (a) Electrodes are placed on the patient’s chest to record the electrical event Electrocardiography. (a) Electrodes are placed on the patient’s chest to record the electrical event
Antibody techniques. (b) An ELISA to test for the presence of herpes simplex virus (HSV Antibody techniques. (b) An ELISA to test for the presence of herpes simplex virus (HSV
Preparing a Urine Specimen for Microscopic Examination (for Classroom Evaluation Only) Preparing a Urine Specimen for Microscopic Examination (for Classroom Evaluation Only)
The Wisconsin Card Sorting Test. This woman is just starting the test. If she places the first card ... The Wisconsin Card Sorting Test. This woman is just starting the test. If she places the first card ...
Diversity in hemoglobin structures Diversity in hemoglobin structures
Video: Introduction to Tuberculosis

For a complete list of videos, visit our video library