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Author Question: An acute leukemia patient presents with blast morphology that is of neutrophil lineage with Auer ... (Read 37 times)

cool

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on: Jun 25, 2018
An acute leukemia patient presents with blast morphology that is of neutrophil lineage with Auer rods and pseudo-Pelger-Hut nuclei, myeloperoxidase, and Sudan Black B.
 
  Cytogenetic analysis reveals a t(8;21)(q22;q22) translocation in the majority of the blasts.
  Which classification of AML best fits this morphology, immunophenotyping, and cytochemistry? Which classification of AML best fits this morphology, immunophenotyping, and cytochemistry?
 
  a. AML not otherwise categorized
  b. AML with multilineage dysplasia
  c. AML with recurrent genetic abnormalities
  d. AML, therapy-related

Question 2

A patient presents with acute leukemia with blasts identified by a positive CD34, CD13, and CD33. Less than 3 of the blasts stain positive for MPO and SBB. Which category of AML is the most likely diagnosis for this patient?
 
  a. AML minimally differentiated
  b. AML without maturation
  c. Acute myelomonocytic leukemia
  d. Acute erythroid leukemia


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emilymalinowski12

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Reply #1 on: Jun 25, 2018
Answer to Question 1

Correct Answer: C

Answer to Question 2

Correct Answer: A


cool

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Reply 2 on: Jun 25, 2018
Great answer, keep it coming :)

softEldritch

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Reply 3 on: Yesterday
Excellent

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