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Author Question: Explain the significance of the Philadelphia chromosome in ALL. What will be an ideal ... (Read 45 times)

elizabeth18

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on: Jun 25, 2018
Explain the significance of the Philadelphia chromosome in ALL.
 
  What will be an ideal response?

Question 2

The key factor to distinguish relative and absolute polycythemia is that a relative polycythemia is caused by:
 
  a. Increased production of erythrocytes
  b. Decreased amount of serum
  c. Increased production of erythropoietin
  d. Decreased arterial oxygen saturation


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macmac

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Reply #1 on: Jun 25, 2018
Answer to Question 1

Answer: Two different types of proteins are associated with the Philadelphia chromosome. P210 is homologous to the Philadelphia chromosome, therefore representing the conversion of CML into blast crisis. The second protein, P190, has a probable linkage to de novo acute leukemias such as ALL.

Answer to Question 2

Correct Answer: B


elizabeth18

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Reply 2 on: Jun 25, 2018
Thanks for the timely response, appreciate it

momolu

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Reply 3 on: Yesterday
YES! Correct, THANKS for helping me on my review

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