Bordetella pertussis is characterized by rapid peripheral lymphocytosis and decreased cellularity of the lymph nodes. What can explain this phenomenon?
a. Loss of homing of B cells to lymphoid tissues
b. Loss of homing of T cells to lymphoid tissue
c. Abnormal homing of lymphocytes to the bone marrow
d. Increase of L-selectin expression by T cells
Question 2
A negative heterophile antibody test in a patient with symptoms of infectious mononucleosis could be caused by what factor if the patient is being treated for cancer?
a. Infection by another virus
b. Level of the antibody not high enough to be detected
c. Immunosuppressed antibody response
d. CMV infection
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