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Author Question: Which of the following does not support the diagnosis of G6PD deficiency? a. Presence of Heinz ... (Read 13 times)

JGIBBSON

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on: Jun 25, 2018
Which of the following does not support the diagnosis of G6PD deficiency?
 
  a. Presence of Heinz bodies with new methylene blue stain
  b. Reticulocytosis
  c. Hemolytic morphology during oxidative event
  d. Decreased mean cell volume

Question 2

Explain why patients with HS typically have an MCHC >36.
 
  What will be an ideal response?


fdliggud

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Reply #1 on: Jun 25, 2018
Answer to Question 1

Correct Answer: D

Answer to Question 2

Answer: Spherocytes have decreased surface-to-volume ratio (decreased membrane with normal hemoglobin content). This accounts for the elevated MCHC result.


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