Which of the following puts a patient taking chloramphenicol at risk for developing aplastic anemia?
a. The drug promotes an immune response against stem cells.
b. The drug is toxic to the bone marrow.
c. The drug results in stem cell resistance to essential cytokines.
d. The drug causes decreased cytokine production.
Question 2
How can infection with the Epstein-Barr virus (EBV) lead to aplastic anemia?
a. EBV causes defects in precursor cells.
b. EBV infects stem cells, and an immune response to destroy the stem cells is initiated.
c. EBV creates immune complexes on the surface of the stem cell that damages it.
d. Infection with the virus shuts down cytokine production by macrophages.
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